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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3cde54206d50672a9000346a11e588202620030acaf822e30eebfab3b3819fc' 
  AND token = 'qk1RJnZx37EgpkOtMKt1jQk4Hm71xskOSW6AM/xZ6E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}