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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f5492627b0d3f7bebd2f899eb80445c25b8790b4463ce6417e395d26626b25' 
  AND token = 'GERld7Y0m67RLjcGq0a892LNMgCVrTH1kzOutAgJN+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}