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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f28878148d03ac3c05de2c44c7d5b1abf02d4a3b195029909e1a4be3434e484' 
  AND token = 'gdZn8DRPg1+w6/Mbyd25TMKc4Tx2ZlePuJf9JLbQnWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}