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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dad3f7e53e443002f83b6e637212f908bd67b6b249585712ee5517c070e677a' 
  AND token = 'fjzlkEP+/1tA4WP9+nWUPZ3/XZ/86S8eo0KdVwBDsNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}