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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3189c5e6a79d91c5bc5b4e57c532ebb26ed4306dac93a09d4148a74be47803df' 
  AND token = 'WTuIh7/wCnoB9CGKkrIj1+eJ4Nf4GBd+LmevrskxDMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}