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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61bdb24c12691937562418afc4ea36754a4f05ebd81f318648a1de1204a0e227' 
  AND token = 'Q83/hxmKOSdQ0dxSskBZXZgg7mhIw2MrDYhhn+L2tKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}