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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc87a85e04c80116c6010c2a20e8e65d8e0cbf2995d58532e1b037c81a1e2814' 
  AND token = 'tigStwTIW1Zq0qyWWzq0lA4wLGBRsFV13XqphmFMrro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}