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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5027cb4dc386ab80f68ccae8e4ec5e94258c5ed3317d5a6ec0b949eb380e534' 
  AND token = 'YUquNJuSDtBY0p1sLNaUOFOYTCZjN7BsCGsChliUqXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}