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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe21f1be573b9a12edf6b2c90c76db96803683a5c319dc695cc7fccdabdf5ed' 
  AND token = 'm9ek7mw6/I3JoREl0ZJaYnkpntxZRNdsS9JZey+PYKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}