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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7743fb8cf68f55754d19d7ddc8d8d8b04a590defcc9528c30ab0b2c6446482' 
  AND token = 'DT1R8JpsBEPRc4O7GwYKxK2NaiV1pS2DOLA1SaYyKlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}