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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f3f4327559d92d5a54e7b0e23254e2c14876f47fa319cf7b687b1671fc0185' 
  AND token = 'TL3J03DP4qPRxM8GQIMR9xxOlTYImpcBrfRoDd/5t5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}