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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a105f87edcfcebf1e631855e56a97dcad9bd8ea6b9c32ea653a37abb358df9b7' 
  AND token = 'p0X4fJT7RvcykKD/kH1Y+8XsOWifPZV2I5YUzkNA4+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}