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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb545d616dea79e78baf14770e7358fbdd8c56db05e41288608fbe19c53e781' 
  AND token = 'Sk5ROr5Myxpx2jxL6slLGjapkU2Y68m+N60Ec1ZdIOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}