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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf3a7b66c61eaf97a28eddbeef071b295a343f6b255acb2ed560bafb0ebbe36' 
  AND token = 'R3ouj3nWYXWA7/d1Jbvo6Lge/D5rx01qoJOOKdkmx9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}