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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaa016373f39947771da4b1c6601e59d03a6823656950bb0d80291e5b6d4d462' 
  AND token = '4M/uDh2w3MBC1E3enDnH4Xkp0TSvWvNlNSaoJdIVj4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}