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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e59f4221017a799a2be0ac54e4c53bf109c8e5ca02549546481d0e70d892de1d' 
  AND token = 'TIsydCc9IhivoHA+0VXzRQJXdq1q/YhM7RxvsIXWwWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}