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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b5c14ca2628f4dd8f00dc902cd0fb9c5a5985355e448df83201293fbfc9e95' 
  AND token = 'yWaHPzDQ/QV0SBpw5DLMRU1K9OZOyliYCqYc4bLwQ0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}