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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145d70ade879d7db28d668f1ca1f3af75a6e4bfbaefe71b5249f89ebd9357d56' 
  AND token = 'X5FIof99RpdOMyAsBX5fgPri9SQoORy/Lb+lQ7Pl6r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}