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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddb605364d091157ad3d6aaa3e969f209cbc4665dc88cf0e61d92697febd86d' 
  AND token = 'p1NcrJgKbEFGl5sxQMcDbGNLwCUndOlQToy8zJ45M74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}