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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0f3e5e163128c32eca4d71292284dbad685017a6e17c13a308dceeb21e39080' 
  AND token = 'gEV/hBr+CBl0FkiEHrpFxO2nh9aj0HKxjoDOK2qMGwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}