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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e4e71a4af64c083d8fe6c2bdb4bb262c121b3cf06b6f13775266e1758325dd' 
  AND token = 'o0z5Rq32aCkdWKaZ6esOjvpNfqb2wb/f0hTVN0m+cOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}