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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd101204de59362d8c6893e1980d737f2527eaeb7727c6984e6a070a213de3e64' 
  AND token = 'hsLWxflUhutGVbvmF9yy8n2xBqZ9+vnhsxPKlNwa3Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}