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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c64fc7619179245be9084be2665a383ff1ee9d6b63bc62a338f373441d124c4e' 
  AND token = 'sPiHW4NSRotV8bBVH0E4YoHD8GxUUNnKT5+qOWCAW18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}