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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24f3f10f6e14a46a2ab568cf70a20958d271a420b3089b1a445d9836afc7a430' 
  AND token = 'sDV+DH48AOWVmAwxA0/titeEJPqj5jsRqR++HcXrxn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}