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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105f10d576ca2dda4e6aa70222c1a743e28dbaad26f797d4131d0445441a10b2' 
  AND token = '5Br+mjhK73LRbisScZhU0d06MdGvfpXt3KCiPKmS8r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}