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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffb963b1c77096348ef5673207fcdabf760f98f8b535983ddb2946548f7053d' 
  AND token = 'Sy3P5hhmAgMn65D+yA61A+k6qo4meA394QmWAvvpsDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}