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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e35513cbe6865e2eb97f6ec4dc5ca86c4bb41f4a453c024964a21e52d1bee43' 
  AND token = 'vEkM17TyDPaLIfMFDc/rQ+ID5/8eGr7ImOhhHW6iQ2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}