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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd153368663f1bdbf926b607bbd784103d7dae6a33c978f323004a89ca9104a75' 
  AND token = '1icchel6T7JVg71qleRTgXN4FjqryZZq1+eqQkspySQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}