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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89562c8fd70f1a9f4235c703aa7d09f4a80c0a35c1dba58fee8c4c959c22f877' 
  AND token = 'P/MYwGIkQZfX1XFvsBeAhwxNPxyKQ5wFQXHDl5OnJw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}