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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5611ad3809aafbd05b1c0f3e9aa26ae43e8186a707a89de0cdb395aefc90e1' 
  AND token = 'zUop+z5hEKhUNcNbQRHSigbWaHhnWKCCs575Ewsa7VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}