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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d09282978cbd350045406ea8c6f0aaf5a4fc8d6c1b4181b491a89d25988dd4d' 
  AND token = 'PDtSvuJD3IdV0+Zx9QZBNfsAcRrWdf0Kjk6QngHxLlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}