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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a69192d82d62c821ee3ca7c78455e88b5e179aee22f644f11890858d0d0cbaa' 
  AND token = 'iRvy4waLeeeskzc535Be+igNpqj7U03Ir+R9IXffMc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}