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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a69afed299049efd2260b2b21dd8bf1b1915ffcc03801f4030f203ed873cb71e' 
  AND token = 'o5dr46jEelJyVweNrnjuJzsc4DarxLgFvUGgXcg7hmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}