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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4076411d7f6612fc5e2fee6dc5a365748aa8c635456c993fb250499ebc202e27' 
  AND token = 'D9O9Ht7jw7V96HtRKfAab0TLtFDeCWQVW0G0U4zvoL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}