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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d6297dbe615788335c547a288415aae7f2eb90341c04c97d6c3468ca5395ed' 
  AND token = 'V5GXAllJo/H5IQ7qqMKz+HdFCoR1MrN3yisI7Z0qsd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}