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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51069aeed66dae0be4719f98432aad4ca52dce36695ca3fb02f7f38a19d1e026' 
  AND token = '+075j8xvmNWGQDwtxejge2KcIqscEDtPAokyYLULN+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}