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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '371e5d1fb855d5d741fc2ad8a80064ca60b4d1de8c354ad7d0d491aff9a04c81' 
  AND token = '+MW16pmVvTBVkoyU4IGzCOHBazvkTtwQBHNVjxZP1/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}