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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c4dd704dbe2eac09b0858cd83dfecb0b3196ac2cce93159a531d60ea9de643a' 
  AND token = 'WLj+IO5gK7XYAceyds7aJnPKoXFZJIwxf0c0s9OKIRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}