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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c95bea7d867e112c9eac3c05858e942a648cee105a8f7447b813c896d77371a' 
  AND token = '4hDyx96Rr+LmxyJOEMyQprhqVjHRmfN6PJfG9kAY7JY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}