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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52866a79c53d07f7eaf78953f38421bbe4458048c8e88e68f1d8e7b8c28ab6f7' 
  AND token = 'XZCW2+65A2LcDab9livzC/zdSLqWqctW8L6G/VCVigI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}