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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa3218f149f860bfdbaf7e316c62d1c6936cb42f8e2e26c218ad406eb23d1e3' 
  AND token = '+1sPAcZ9+SAUse/vp8GYZW0/1+Mx06zRYEqZFCPm47E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}