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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165870f9f119666012ac292125216e2b1c8e10f40c2b49b23795d3b9b37a9f1e' 
  AND token = 'RNmOeU8KjyeGBbCco+gb8wc0rv2oSKXHVYyRqIBkQ2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}