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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463d8844b2a5de4eb44c3c804b50a9b13f5e396e79ef4173389f02affbd118bd' 
  AND token = 'ff3r/gNvtx0d1vHk1JsBhb3yoYCNT7G0+ufg4I4iQ90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}