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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd7d12c759bb3760582c8397d11bda975014ebf74f99c84282a1d541e91541f1' 
  AND token = 'AjYXdr3a7tkpUGxH9nIznVgLkkCcwTtMgXEM/XUHh/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}