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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a00f65148dcf051967decae84d31981695e981c62aa7c30ba5c0b20c5dc4fa' 
  AND token = 'gNAKqBAKJkDl2t4zIJr2VGcK3h2IFceLzdqNJoE1MO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}