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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38cf7788a726a6356772d36011ef5c272866558b2a6037b31363f53b18ac4982' 
  AND token = 'MDkRG90g00ROtcF+pG7CwQUcOWc9IoIhDe6yR/D8GsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}