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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110a36d84e029f19391f626fa1dc5ebc040207711b9773484b8b09c0e01034cd' 
  AND token = 'YMxvOs2dYpjMT8O0ioXkxXEyuSJArVuzXMmMTzsbTuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}