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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14f41f6d7a77bb0b34251761e40c9b78f34d891a45474b1a189af12e71216a7e' 
  AND token = 'xUTze99XEE+ClEiLhNl40ARBylYfXVZZL7ls1nm2ioc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}