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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f8eff9cff8405863ec88795582bb6464564b4352fbc5291803cada8f4d6818' 
  AND token = '4MR1PI9KaY5lITWLpoC1NMo6fd1e22KIweEpxtn8jS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}