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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '442b199c16be46616e02f50381bdcfcafd703e9c68b41be2b0ae807af7f02e6a' 
  AND token = 'J1YP9/17+XSH8Xp5427TLBTrH3LpvIXDRIv4OMnSrXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}